RECENT PUBLICATIONS

2024年

59. Otsubo, K., Sakashita, N., Nishimoto, Y., Sato, Y., Tsutsui, T., Kobayashi, K., Suzuki, K., and Segi-Nishida, E*. Role of desmoplakin in supporting neuronal activity, neurogenic processes, and emotional-related behaviors in the dentate gyrus. Front Neurosci., 18, 1418058. 2024. doi:10.3389/fnins.2024.1418058

2023年

58. Kasakura N., Murata Y., Shindo A., Kitaoaka S., Furuyashiki T., Suzuki K., Segi-Nishida E*., Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process. Front. Neurosci., 17, 1178555. 2023. doi:1 0.3389/fnins.2023.1178555

57. Matsuura S., Nishimoto Y., Endo A., Shiraki H., Suzuki K., Segi-Nishida E*., Hippocampal inflammation and gene expression changes in peripheral lipopolysaccharide challenged mice showing sickness and anxiety-like behaviors. Biol. Pharm. Bull., 46, 1-9. 2023.

2022年

56. Segi-Nishida E*., Suzuki K., Regulation of adult-born and mature neurons in stress response and antidepressant action in the dentate gyrus of the hippocampus. Neuroscience Res. doi: 10.1016/j.neures.2022.08.010. 2022 in press

55. Kondo, M., Okazaki, H., Nakayama, K., Hohjoh, H., Nakagawa, K., Segi-Nishida, E., Hasegawa, H., Characterization of Astrocytes in the Minocycline-Administered Mouse Photothrombotic Ischemic Stroke Model. Neurochem Res. 47(9) 2839-2855. 2022. doi:10.1007/s11064-022-03703-z

54. Kobayashi, K., Shikano, K., Kuroiwa, M., Horikawa, M., Ito, W., Nishi, A., Segi-Nishida, E., Suzuki, H., Noradrenaline activation of hippocampal dopamine D1 receptors promotes antidepressant effects. Proc Natl Acad Sci USA 119(33), 2022. e2117903119. doi:10.1073/pnas.2117903119

53. Yoshioka, T., Yamada, D., Kobayashi, R., Segi-Nishida, E., Saitoh, A., Chronic vicarious social defeat stress attenuates new-born neuronal cell survival in mouse hippocampus. Behav Brain Res 416, 113536. 2022. doi:10.1016/j.bbr.2021.113536

2021年

52. Hasegawa, H., Kondo, M., Hohjoh, H., Nakayama,K., Segi-Nishida, E. C-C Chemokine Receptor 5 (CCR5) Expression in the Infarct Brain of the Photothrombosis Mouse Model. BPB Reports 3:208-215. 2020. doi: https://doi.org/10.1248/bpbreports.3.6_208

51. Takefusa, M., Kubo, Y., Ohno, M. and Segi-Nishida, E*. Electroconvulsive seizures lead to lipolytic-induced gene expression changes in mediobasal hypothalamus and decreased white adipose tissue mass. Neuropsychopharmacol Rep. 2021. doi: 10.1002/npr2.12156.(*, corresponding author)

2020年

50. Koinuma S, Negishi R, Nomura R, Sato K, Kojima T, Segi-Nishida E, Goitsuka R, Iwakura Y, Wada N, Koriyama Y, Kiryu-Seo S, Kiyama H, Nakamura T. TC10, a Rho family GTPase, is required for efficient axon regeneration in a neuron-autonomous manner. J Neurochem. 2020. https://doi.org/10.1111/jnc.15235

49. Hohjoh H, Horikawa I, Nakagawa K, Segi-Nishida E, Hasegawa H. Induced mRNA expression of matrix metalloproteinases Mmp-3, Mmp-12, and Mmp-13 in the infarct cerebral cortex of photothrombosis model mice. Neurosci Lett. 739:135406. 2020. doi: 10.1016/j.neulet.2020.135406.

48. Kobayashi K, Mikahara Y, Murata Y, Morita D, Matsuura S, Segi-Nishida E, Suzuki H. Predominant Role of Serotonin at the Hippocampal Mossy Fiber Synapse with Redundant Monoaminergic Modulation. iScience. 23(4): 101025. 2020. doi: 10.1016/j.isci.2020.101025

2019年

47.Kobayashi Y, Segi-Nishida E. Search for factors contributing to resistance to the electroconvulsive seizure treatment model using adrenocorticotrophic hormone-treated mice. Pharmacol Biochem Behav. 186:172767, 2019. doi:10.1016/j.pbb.2019.172767 (, corresponding author)

46. Ueno M, Sugimoto M, Ohtsubo K, Sakai N, Endoh A, Shikano K, Imoto Y, Segi-Nishida E. The effect of electroconvulsive seizure on survival, neuronal differentiation, and expression of the maturation marker in the adult mouse hippocampus. J Neurochem. 149(4):488-498, 2019. doi: 10.1111/jnc.14691(, corresponding author)

45. Kitadate Y, Jorg DJ, Tokue M, Maruyama A, Ichikawa R, Tsuchiya S, Segi-Nishida E, Nakagawa T, Uchida A, Kimura-Yoshida C, Mizuno S, Sugiyama F, Azami T, Ema M, Noda C, Kobayashi S, Matsuo I, Kanai Y, Nagasawa T, Sugimoto Y, Takahashi S, Simons BD, Yoshida S. Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche. Cell Stem Cell. 24(1):79-92.e6. 2019. doi:10.1016/j.stem.2018.11.013

2018年

44. Nie X, Kitaoka S, Tanaka K, Segi-Nishida E, Imoto Y, Ogawa A, Nakano F, Tomohiro A, Nakayama K, Taniguchi M, Mimori-Kiyosue Y, Kakizuka A, Narumiya S, Furuyashiki T. The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation. Neuron. 99(3):464-479. 2018. doi: 10.1016/j.neuron.2018.06.035.

43. Hirono J, Sanaki H, Kitada K, Sada H, Suzuki A, Lie LK, Segi-Nishida E, Nakagawa K, Hasegawa H: Expression of tissue inhibitor of metalloproteinases and matrix metalloproteinases in the ischemic brain of photothrombosis model mice. Neuroreport 29(3):174-180. 2018. doi: 10.1097/WNR.0000000000000946.

2017年

42. Segi-Nishida E*: The effect of serotonin-targeting antidepressants on neurogenesis and neuronal maturation of the hippocampus mediated via 5-HT1A and 5-HT4 receptors. Front. Cell. Neurosci. 11:142, 2017 doi: 10.3389/fncel.2017.00142

41. Imoto Y., Segi-Nishida E*, Suzuki H., Kobayashi K*: Rapid and stable changes in maturation-related phenotypes of the adult hippocampal neurons by electroconvulsive treatment. Mol Brain, 10:8, 2017, doi: 10.1186/s13041-017-0288-9. (*, corresponding authors)

40. Kobayashi K., Imoto Y., Yamamoto F., Kawasaki M., Ueno M., Segi-Nishida E, Suzuki N.: Rapid and lasting enhancement of dopaminergic modulation at the hippocampal mossy fiber synapse by electroconvulsive treatment. J Neurophysiol, 117(1):284-289. 2017, doi: 10.1152/jn.00740.2016

2015年

39. Imoto Y., Kira T., Sukeno M., Nishitani N., Nagayasu K., Nakagawa T., Kaneko S., Kobayashi K., Segi-Nishida E*: Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus. Mol Brain, 8 (1): 29, 2015 (*, corresponding author)

東京理科大学着任前

2014年

38. Tani, Y., Isobe, Y., Imoto, Y., Segi-Nishida, E., Sugimoto, Y., Arai, H., and Arita, M: Eosinophils control the resolution of inflammation and draining lymph node hypertrophy through the proresolving mediators and CXCL13 pathway in mice. FASEB J 28(9):4036-4043, 2014.

37. Morimoto K, Shirata N, Taketomi Y, Tsuchiya S, Segi-Nishida E, Inazumi T, Kabashima K, Tanaka S, Murakami M, Narumiya S, Sugimoto Y: Prostaglandin E2-EP3 signaling induces inflammatory swelling by mast cell activation. J Immunology 192:1130-1137, 2014

2013年

36. Segi-Nishida E*, Sukeno M, Imoto Y, Kira T, Sakaida M, Tsuchiya S, Sugimoto Y, Okuno Y: Electroconvulsive seizure activate anorexigenic signals in the ventromedial nuclei of the hypothalamus. Neuropharmacology, 71:164-173, 2013.(*, corresponding author)

35. Sakaida M, Sukeno M, Imoto Y, Tsuchiya S, Sugimoto Y, Okuno Y, Segi-Nishida E*: Electroconvulsive seizure-induced changes in gene expression in the mouse hypothalamic paraventricular nucleus. J Psychopharmacology, 27(11):1058-1069, 2013 (*, corresponding author)

2012年

35. Tanaka K, Furuyashiki T, Kitaoka S, Senzai Y, Imoto Y, Segi-Nishida E, Deguchi Y, Breyer RM, Breyer MD, Narumiya S: Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice. J Neurosci, 32:4319-4329, 2012.

2011年

34. Inazumi T, Shirata N, Morimoto K, Takano H, Segi-Nishida E, Sugimoto Y: Prostaglandin E-EP4 signaling suppresses adipocyte differentiation in mouse embryonic fibroblasts via an autocrine mechanism. J Lipid Res, 52:1500-1508, 2011.

33. Segi-Nishida E: Exploration of new molecular mechanisms for antidepressant actions of electroconvulsive seizure. Biol Pharm Bull, 34:939-944, 2011.

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